before setup your Mozilla Thunderbird, pls make sure you have below information
incoming mail server : mail yourdomain.com
outgoing smtp server : smtp.yourdomain.com
email address : username@yourdomain.com
password : *****************
This tutorial will help you set up the Mozilla Thunderbird™ e-mail client to work with your e-mail account.
To Set Up Your E-mail Account in Mozilla Thunderbird
In Mozilla Thunderbird, from the Tools menu select Account Settings.
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Select Email account, and then click Next.
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Enter your name and e-mail address.
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Select POP or IMAP as the type of incoming server you are using. Your incoming server is mail.yourdomain.com for POP, or imap.yourdomain.com for IMAP. Click Next.
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Enter your e-mail address for the Incoming User Name, and Outgoing User Name. Click Next
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Enter a name for your email account and click Next.
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Verify your account information and click Finish.
In the Account Settings window, select Outgoing Server listed below your new account.
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Type smtp.yourdomain.com for the Server Name and change the Port setting to 465.
Select Use name and password and enter your e-mail address. Thunderbird will ask you for your password the first time you try to send mail. Click OK.